The new-ish poster for Lost's final season contains hieroglyphics, so the TV lovers at Popular Mechanics sent it to Dr. James Allen, Wilbour Professor of Egyptology and Chair of Egyptology and Ancient Western Asian Studies at Brown University, who analyzed the symbols and had this answer:
"The hieroglyphs spell out two Egyptian words, meaning 'Who is the guide?' or 'Who is the leader?"
Oops, forgot to put a "spoiler alert" on that. Sorry! [Popular Mechanics]