Watch Helen Mirren Seduce Billy Crystal in When Harry Met Sally 2


Funny or Die went big on this one, recruiting Mirren, Crystal, Rob Reiner, Adam Scott, Maya Rudolph, Mike O'Malley, Rob Riggle, and ... Mike Tyson. Oh, plus all the fake blood and organs available in the greater–Los Angeles area. Can you guess why? (You can guess why.)

[Funny or Die]