Rooney Mara is taking over for Blake Lively in Steven Soderbergh's upcoming psychopharmacology drama Side Effects (formerly known as The Bitter Pill, and then as The Side Effects), according to Deadline, following rumors that the producer had backed out of financing the film because of Lively's casting. Mara will play an anxiety-prone pill abuser who's dreading her husband's release from prison; Channing Tatum will play her husband, and Jude Law and Catherine Zeta-Jones will play two of her doctors. Financing for the film fell apart last week — perhaps indicating a lack of confidence in Lively — but Mara's casting will likely set things back in motion. More important, it raises the question of why there haven't been more (any?) Gossip Girl With the Dragon Tattoo mash-ups.